PBG  R Documentation 
Effect of Phenylbiguanide on Blood Pressure
Description
The PBG
data frame has 60 rows and 5 columns.
Format
This data frame contains the following columns:
 deltaBP

a numeric vector
 dose

a numeric vector
 Run

an ordered factor with levels
T5
<T4
<T3
<T2
<T1
<P5
<P3
<P2
<P4
<P1
 Treatment

a factor with levels
MDL 72222
Placebo
 Rabbit

an ordered factor with levels
5
<3
<2
<4
<1
Details
Data on an experiment to examine the effect of a antagonist MDL 72222 on the change in blood pressure experienced with increasing dosage of phenylbiguanide are described in Ludbrook (1994) and analyzed in Venables and Ripley (2002, section 10.3). Each of five rabbits was exposed to increasing doses of phenylbiguanide after having either a placebo or the HD5antagonist MDL 72222 administered.
Source
Pinheiro, J. C. and Bates, D. M. (2000), MixedEffects Models in S and SPLUS, Springer, New York. (Appendix A.21)
Venables, W. N. and Ripley, B. D. (2002) Modern Applied Statistics with S (4th ed), Springer, New York.
Ludbrook, J. (1994), Repeated measurements and multiple comparisons in cardiovascular research, Cardiovascular Research, 28, 303311.