Metadata Holding Grading Criteria for NCI-CTCAEv6 using SI unit where applicable

Description

Metadata Holding Grading Criteria for NCI-CTCAEv6 using SI unit where applicable

Usage

atoxgr_criteria_ctcv6

Format

An object of class data.frame with 43 rows and 13 columns.

Details

This metadata has its origin in the ADLB Grading Spec json file data-raw/adlb_grading/ncictcaev6.json. The variables GRADE_NA_CODE, GRADE_4_CODE, GRADE_3_CODE, GRADE_2_CODE and GRADE_1_CODE in the json file are combined to create GRADE_CRITERIA_CODE, and then dropped from metadata. The dataset contains the following columns:

• SOC: variable to hold the SOC of the lab test criteria.

• TERM: variable to hold the term describing the criteria applied to a particular lab test, eg. 'Anemia' or 'INR Increased'. Note: the variable is case insensitive.

• ⁠Grade 1⁠: Criteria defining lab value as Grade 1.

• ⁠Grade 2⁠: Criteria defining lab value as Grade 2.

• ⁠Grade 3⁠: Criteria defining lab value as Grade 3.

• ⁠Grade 4⁠: Criteria defining lab value as Grade 4.

• ⁠Grade 5⁠: Criteria defining lab value as Grade 5.

• Definition: Holds the definition of the lab test abnormality.

• GRADE_CRITERIA_CODE: variable to hold code that creates grade based on defined criteria.

• UNIT_CHECK: variable to hold SI unit of particular lab test. Used to check against input data if criteria is based on absolute values.

• VAR_CHECK: List of variables required to implement lab grade criteria. Use to check against input data.

• DIRECTION: variable to hold the direction of the abnormality of a particular lab test value. 'L' is for LOW values, 'H' is for HIGH values. Note: the variable is case insensitive.

• COMMENT: Holds any information regarding rationale behind implementation of grading criteria.

Note: Variables SOC, TERM, ⁠Grade 1⁠, ⁠Grade 2⁠,⁠Grade 3⁠,⁠Grade 4⁠,⁠Grade 5⁠, Definition are from the source document on NCI-CTC website defining the grading criteria. Common Terminology Criteria for Adverse Events (CTCAE)v6.0 From these variables only 'TERM' is used in the {admiral} code, the rest are for information and traceability only.

See Also

Other metadata: atoxgr_criteria_ctcv4, atoxgr_criteria_ctcv4_uscv, atoxgr_criteria_ctcv5, atoxgr_criteria_ctcv5_uscv, atoxgr_criteria_ctcv6_uscv, atoxgr_criteria_daids, atoxgr_criteria_daids_uscv, country_code_lookup, dose_freq_lookup