gehanR Documentation

Remission Times of Leukaemia Patients

Description

A data frame from a trial of 42 leukaemia patients. Some were treated with the drug 6-mercaptopurine and the rest are controls. The trial was designed as matched pairs, both withdrawn from the trial when either came out of remission.

Usage

gehan

Format

This data frame contains the following columns:

pair

label for pair.

time

remission time in weeks.

cens

censoring, 0/1.

treat

treatment, control or 6-MP.

Source

Cox, D. R. and Oakes, D. (1984) Analysis of Survival Data. Chapman & Hall, p. 7. Taken from

Gehan, E.A. (1965) A generalized Wilcoxon test for comparing arbitrarily single-censored samples. Biometrika 52, 203–233.

References

Venables, W. N. and Ripley, B. D. (2002) Modern Applied Statistics with S. Fourth edition. Springer.

Examples

library(survival)
gehan.surv <- survfit(Surv(time, cens) ~ treat, data = gehan,
     conf.type = "log-log")
summary(gehan.surv)
survreg(Surv(time, cens) ~ factor(pair) + treat, gehan, dist = "exponential")
summary(survreg(Surv(time, cens) ~ treat, gehan, dist = "exponential"))
summary(survreg(Surv(time, cens) ~ treat, gehan))
gehan.cox <- coxph(Surv(time, cens) ~ treat, gehan)
summary(gehan.cox)