ahdR Documentation

Methylprednisolone data

Description

Data from a longitudinal study examining the effectiveness of Methylprednisolone as a treatment for patients with severe alcoholic hepatitis. Subjects were randomly assigned to a treatment (31 received a placebo, 35 received the treatment) and serum bilirubin was measures each week for four weeks.

Usage

data(ahd)

Format

A data frame with 330 observations on the following 5 variables:

treatment

The treatment a subject received - a factor. Levels are placebo and treated.

subject

Subject ID - a factor.

week

Week of the study (0–4) - the time variable.

sbvalue

Serum bilirubin level (in μmol/L).

baseline

A subject's serum bilirubin level at week 0.

Source

Vonesh, E. F. and Chinchilli, V. M. (1997) Linear and Nonlinear Models for the Analysis of Repeated Measurements. Marcel Dekker, New York.

References

Carithers, R. L., Herlong, H. F., Diehl, A. M., Shaw, E. W., Combes, B., Fallon, H. J. & Maddrey, W. C. (1989) Methylprednisolone therapy in patients with severe alcoholic hepatitis. Annals of Internal Medicine, 110(9), 685–690.